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Home to Mayo Clinic and located in the United States’ Upper Midwest region, Rochester, Minnesota is a thriving city of just over 100,000. Consistently rated as one of the best cities to live in the U.S., Rochester is also a welcoming destination for visitors. Distinguished by its culture of caring, spirit of innovation, and fascinating history, Rochester, MN is renowned for its scenic beauty, relaxing pace, and abundant dining, shopping, and entertainment options. Order a free visitor's guide to discover more of what Rochester, MN has to offer.